Cardiovascular Disease and NASH

Authors

  • Erika Rabelo Forte de Siqueir Author
  • Leila Maria Moreira Beltrao Pereira Author
  • Arun Jayant Sanya Author
  • Arun Jayant Sanya Author

Keywords:

NAFLD: Non-alcoholic fatty liver disease, Non-alcoholic steatohepatitis (NASH), CVD: Cardiovascular disease, MetS: Metabolic Syndrome, AF: Atrial Fibrillation, CAC: Coronary Artery Calcium;, CT: Computed Tomography, FFAs: Free Fatty Acids, LDL-C: Low-density Lipoprotein-Cholesterol, HMGCR: HMG CoA Reductase, VLDL: Very-low-density lipoprotein, CAD: Coronary Artery Disease

Abstract

Non-alcoholic fatty liver disease (NAFLD) and Non-alcoholic steatohepatitis (NASH) 
are associated with cardiovascular events and Metabolic Syndrome (MetS). NAFLD is considered to be a hepatic manifestation of MetS and has become an important public health issue 
because of its high prevalence. It is currently being considered an independent Cardiovascular 
disease (CVD) risk factor. In this clinical review, we will briefly review the mechanisms linking 
NAFLD to the complement system, endothelial dysfunction and the atherosclerosis. 

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Published

2015-07-29