Treatment of Stage I Seminoma

Abstract

Stage I testicular seminoma is a curable condition. The primary treatment is high inguinal
orchiectomy. The treatment options after surgery includes radiotherapy, chemotherapy
with single agent carboplatin and active surveillance. Radiotherapy has evolved over the past
decades with reduced treatment volume and radiation dose without compromising the outcome.
Para aortic strip radiation 20 Gy in 10 fractions is equivalent to single agent carboplatin. Active
surveillance is an acceptable approach for patients without adverse factors. There is no data
comparing treatment versus active surveillance till date. This article reviews the evidences for
each approach.