Evaluation of Cardio-Ankle Vascular Index and Influencing Factors in Natural Population of She Minority in China

Abstract

Objective: The present study was designed to investigate the influencing factor of cardio-ankle 
vascular index (CAVI) in natural population of She minority in China.
Methods: Five hundred and twenty-four subjects were enrolled into our study (male 227 and 
female 297). Main analyzing indexes included vascular related markers namely of CAVI and 
carotid artery intima-media thickness (CIMT) and blood markers.
Results: Systolic blood pressure (SBP) and diastolic blood pressure (DBP) were high in the entire population (150.08±23.32 mmHg, 91.15±12.42 mmHg). CAVI, left CIMT and right CIMT 
were normal. Univariate analysis showed CAVI was positively correlated with age, waist hip 
ratio (WHR), SBP, DBP, pulse pressure (PP), blood urea nitrogen (BUN), serum creatinine 
(Cr), fasting plasma glucose (FPG), triglyceride (TG), total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), high sensitive C reactive protein (hs-CRP), left CIMT and right 
CIMT (r=0.570, 0.240, 0.512, 0.372, 0.459, 0.231, 0.095, 0.182, 0.158, 0.164, 0.167, 0.169, 
0.395, 0.407, all p<0.05). Multivariate linear regression analysis (selected factors including 
age, heart rate (HR), body mass index (BMI), WHR, SBP, DBP, PP, blood uric acid (UA), 
BUN, Cr, FPG, TC, TG, high density lipoprotein cholesterol (HDL-C), LDL-C, hs-CRP, left 
CIMT and right CIMT) showed that age, SBP, FPG, hs-CRP, TG and Cr were the independent 
related factors of CAVI (adjusted R2
=0.399).
Conclusion: Age, systolic blood pressure, fasting plasma glucose, high sensitive C-reactive
protein, triglyceride and creatinine levels were independent factors of CAVI in natural populations of She minority in China