Explanatory Factors of Gestational Diabetes Pedigree Function of Pima Indian Heritage Women

Abstract

Diabetes pedigree function (DPF) predicts diabetes risk based 
on age and family history, regardless of whether the person 
is diabetic or not. There is little proof to support the notion that 
type 2 diabetes (T2D) is a hereditary condition. In real life, it is 
common for a T2D patient to have T2Ds in one or more family 
members, such as at least one parent or sibling.1,2 Additionally, it is 
observed that a subject’s chance of having T2Ds rises in proportion to the number of members of his or her family who have the 
disease.3,4 Clinical family history of diabetes has been recognized as 
a T2D risk factor and provides genuine genomic data that identifies the interactions between genetic, behavioral, and environmental factors.2,3 To the best of our knowledge, there has been minimal 
research done on the factors that influence DPF. It is intriguing 
to investigate how age, body mass index (BMI), subject type (ST), 
such as diabetic (=2) or non-diabetic (=1), etc., relate to DPF and 
diabetes biomarkers